Pirfenex 400mg Tablet

Dosage form and Strength of Pirfenex 400mg (Pirfenidone) Tablet:
It is a film-coated tablet.
Each film-coated tablet contains Pirfenidone 400mg.

Mechanism Of Action of Pirfenex 400mg (Pirfenidone) Tablet:
It is in a class of medications called pyridones.
It works by blocking the action of a certain natural substance in the body that is involved in causing fibrosis.
It shows both anti-inflammatory and antifibrotic effects.
It inhibits both production and activity of TGF-β which leads to reduction of fibrosis and swelling in lungs.
It slows down the buildup of scar tissue (fibrosis) in the lung by interfering with the ability of cells to make scar tissue.
It could inhibit apoptosis, downregulate ACE receptor's expression, decrease inflammation by several mechanisms and ameliorate oxidative stress and hence protect pneumocytes and other cells from invasion and cytokine storm simultaneously.

Administration of Pirfenex 400mg (Pirfenidone) Tablet:
It is to be used orally.
Do not self-medicate the therapy.
Take it as directed by the Physician.

Therapeutic Use of Pirfenex 400mg (Pirfenidone) Tablet:
It is used in the treatment of Idiopathic Pulmonary Fibrosis (IPF).
It reduces scarring and swelling in the lungs and helps to breathe better.
These medications are called anti-fibrotic agents.
These drugs are approved for patients with mild, moderate and severe IPF.

Usage Instruction of Pirfenex 400mg (Pirfenidone) Tablet:
For oral use only.
It is to be taken with food.
Take it as directed by the Physician.

Side Effects:
Sunburn,
Diarrhoea,
Dizziness,
Skin Rash,
Itching,
Loss of Appetite,
Insomnia,
Headache,
Nausea,
Pain,
Heartburn,
Vomiting.

Safety Precautions:

Alcohol:
It is generally considered safe to use in alcoholic patients.
However, it is advisable to consult a doctor for personalized advice.

Pregnancy:
It is unsafe to use during pregnancy.
It may harm an unborn baby.
Pregnant women should consult their doctor for alternative treatment options.

Lactating Mothers:
The study of the Tablet in Lactating Mothers in not known.
Precaution is necessary while using this medicine.
Lactating mothers should seek medical advice for appropriate alternatives.

Driving:
It may affect the ability to drive, so it is recommended to avoid driving after taking the medication.
Consult your doctor for guidance on driving safety.

Renal Impairment:
It should be used with precautions in Renally Impaired patients.
However, it is important to consult a doctor for proper evaluation and potential dosage adjustments.

Hepatic Impairment:
It should be used with precautions in Hepatically Impaired patients.
However, it is important to consult a doctor for proper evaluation and potential dosage adjustments.

Contraindications:
Known hypersensitivity.





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